I don't believe so would be cool though.
No, because it takes about a hundred years for radiation to cause severe ghoulification, which is why almost every ghoul in the game is like almost 200 years old. As a ghoul, you don't need as much to survive cuz ur half dead, so u live much longer. and after long enough you become a feral ghoul which... just... sucks.
~ What about Moira Brown turning into to a ghoul immediately after you blow up Megaton? ~