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Can I still do the Blood Ties Quest after destroying Megaton?

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I believe you can, but you just won't get the dialogue that Lucy west is supposed to say if she is still alive. just head to Arefu and the guard/"Mayor" will throw a grenadine at you thinking you're an enemy. from then on just keep talking about the "Family", Ian west, the rest of the west family, and the residents of Arefu and eventually you can begin the quest.

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