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Of Course,even though Wolverine Has a healing factor and an adamantium skeleton,he's not immortal.When Magneto ripped the adamantium skeleton from him he became very vulnerable,making many bullets and/or a knife in the head become fatal.A decapitation can work,but it is presumed that if someone puts Wolverine's head close to its body,as his healing factor would keep him alive for a few hours,the head would eventually reattach to his body,or he could be killed in all the conventional ways if BOTH his Admnt. skeleton was removed and his healing factor was disabled.