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How did Christopher Columbus die?

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On May 20, 1506, at about age 55, Columbus died in Valladolid, fairly wealthy from the gold his men had accumulated in Hispaniola. At his death, he was still convinced that his journeys had been along the east coast of Asia. According to a study, published in February 2007, by Antonio Rodriguez Cuartero, Department of Internal Medicine of the University of Granada, he died of a heart attack caused by Reiter's Syndrome (also called reactive arthritis). According to his personal diaries and notes by contemporaries, the symptoms of this illness (burning pain during urination, pain and swelling of the knees, and conjunctivitis) were clearly evident in his last three years.

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