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To get rid of acne you need to low the amount of toxicity in your blood.
To do this you need try and understand what is causing those toxins in the first place and eliminate that cause. The difficulty is that toxins can be caused by such a wide variety of things that it's very difficult to narrow it down.
For example, some people get acne because of the foods they eat, because they have a yeast infection, because they are illergic to something and so on. Some people don't even have high blood toxicity but still get acne - this could be because their filtering organs, or even digestive system, is not working optimally and could do with some kind of cleanse to give it a boot.
It's difficult to describe it all in one answer. Here's a good post that I read recently on the subject: How to clear acne