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The total distance from Washington, DC to Charleston, SC is 452 miles.
This is equivalent to 727 kilometers or 393 nautical miles.
The distance calculator measures the straight line flight distance ("as the crow flies") between points. It uses the great circle formula to compute the travel mileage.
The driving distance from Washington, DC to Charleston, SC is 535 mi with a driving time of about 8 hours 32 mins.