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What can I miss in Vault 101?

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The most important one is the Medicine bobblehead, which permanently raises your Medicine skill by 10. Additionally, there is a Rock-It Launcher schematic (for some reason) in a Very Hard locked safe in the physician's office behind a picture frame. You can't get it when you're leaving the vault, but when you return for the quest "Trouble on the Homefront", you can access it.

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