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What characteristics of Viral replication may help to explain why you do not develop immunity to the common cold?

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Viruses have a high mutation rate compared to single-celled organisms such as bacteria. Even if one were to become immune to a particular virus, eventually it would change enough that your immune system would not "remember" it.

In addition, there are believed to be several hundred viruses that cause the symptoms of the common cold. It is not just one virus that makes you sick each year, but one of many.

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