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It is not necessarily a disease, but more like a side effect of over consumption of Beta-Carotene. It is called "carotenodermia".

Read this wiki article about it:

"The most common side effect of excessive β-carotene consumption is carotenodermia, a harmless condition that presents as a conspicuous orange skin tint arising from deposition of the carotenoid in the outermost layer of the epidermis[3]. High doses of β-carotene have been associated with increased rate of lung cancer among those who smoke.[4]"

Includes CC-BY-SA content from Wikipedia's Beta-Carotene article (authors)

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