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There is no card because every card has its own different effect which can be countered with other cards. You cannot win any ugioh duels with seperate monsters, you must use combinations and strategy.

Well, every cards are useful in some ways and you can't actually determine the best card in Yu-Gi-Oh!. however, in my opinion, Stardust Dragon is the most effective card in yugioh and it can defeat other cards' effects and it suits in almost all type of decks.

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