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Do you mean where is a Silenced 10mm? If you can just kill Mr Burke in Megaton/Tenpenny Towers. He has one, and they are pretty good for sneaky characters. There are other locations though, such as:
- In Marigold Metro Station, which is part of the quest Those!.
- In the caves under Oasis.
- Found in a locked safe in a room near the entrance of the Museum of History's lower halls.
- Some Ghoul residents of Underworld carry this gun.
- Rarely, it can be purchased at Flak and Shrapnel's weapon store in Rivet City or Chief Gustavo in Tenpenny Tower.
- In a safe located in an unmarked sewer south-east from Arlington Library.
- In the entrance to Vault 108, near some blood and Mole Rats.
- In the locked safe in the floor of the ruined ship right next to Hamilton's Hideaway.
- The hotel occupied by the Brotherhood of Steel next to Pennsylvania Avenue Northwest.
- Underwater by a sunken car at the docks nearby Arefu.
- On one of the clones In Vault 108.
- In a locked safe (Very Hard) in The Ninth Circle.
- In one of the locked rooms in Vault 106.
- On the counter of Lock and Load in Paradise Falls (must be stolen)