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- The NX-01 Enterprise was captained by Jonathan Archer.
- The original USS Enterprise had three captains: Robert April, Christopher Pike, and of course, James Kirk.
- The Enterprise-A was also Kirk.
- The Enterprise-B was captained by John Harriman.
- The C was commanded by Rachel Garrett, replaced by Richard Castillo as acting captain.
- Captain Jean-Luc Picard was in charge of the D and E.