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From the episode 'Stewie Loves Lois'

Stewie: Brian loves Olympia Dukakis.

Referencing Olympia Dukakis, the daughter of Greek immigrants, who has starred in many movies. She is also cousin to former (Democratic) presidential candidate Michael Dukakis. Probably Brian would love for for being liberal and also for being an older woman. (Like Lois to Stewie.)

http://www.imdb.com/name/nm0001156/

This could be completely random, but Olympia Dukakis family has names similar to the names of family guy characters, with top of the top characters having very similar names to Olympia Dukakis closest family members, which odds probably suggest this isn't completely random luck.

Olympia Dukakis's family first, (followed by a Family Guy's character)

Husband Louis, (wife Lous)

Child Christina, (child Chris)

Child Peter, (Dad Peter)

Child Stefan, (child Stewie)

So I'm totally speculating here, that Olympia Dukakis's family (or at least their names) might of been some sort of inspiration for Family Guy creates.

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